Publications using 
In Vitro MultiFlow Family of Kits

(High Content Assays)

Interlaboratory Evaluation of a Multiplexed High Information Content In Vitro Genotoxicity Assay

S.M. Bryce1, D.T. Bernacki1, J.C. Bemis1, R.A. Spellman2, M.E. Engel2, M. Schuler2, E. Lorge3, P.T. Heikkinen4, U. Hemmann5, V. Thybaud6, S. Wilde7, N. Queisser7, A. Sutter7, A. Zeller8, M Guérard8, D. Kirkland9, S.D. Dertinger1

1 Litron Laboratories
2 Pfizer Worldwide Research and Development
3 Servier Group
4 Orion Pharma
5 Sanofi-Aventis Deutschland GmbH
6 Sanofi
7 Bayer AG
8 Roche Pharma Research and Early Development
9 Kirkland Consulting

Environmental and Molecular Mutagenesis
Volume 58, Issue 3, April 2017, Pages 146–161
γH2AX and p53 responses in TK6 cells discriminate promutagens and nongenotoxicants in the presence of rat liver S9

D.T. Bernacki1, S.M. Bryce1, J.C. Bemis1, D. Kirkland2, S.D. Dertinger1

1 Litron Laboratories
2 Kirkland Consulting

Environmental and Molecular Mutagenesis
Volume 57, Issue 7, August 2016, Pages 546–558
Genotoxic mode of action predictions from a multiplexed flow cytometric assay and a machine learning approach

S.M. Bryce, D.T. Bernacki, J.C. Bemis, S.D. Dertinger

Litron Laboratories

Environmental and Molecular Mutagenesis
Volume 57, Issue 3, April 2016, Pages 171–189
Interpreting in vitro micronucleus positive results: simple biomarker matrix discriminates clastogens, aneugens, and misleading positive agents

S.M. Bryce1, J.C. Bemis1, J.A. Mereness1, R.A. Spellman2, J. Moss2, D. Dickinson2, M.J. Schuler2, S.D. Dertinger1

1 Litron Laboratories
2 Pfizer Worldwide Research and Development

Environmental and Molecular Mutagenesis
Volume 55, Issue 7, August 2014, Pages 542–555