In Vitro Pig-a Gene
Mutation Analysis


(MutaFlow® Kits)

Measuring DNA Damage
at the Pig-a Locus

This test detects mutations at the Pig-a gene in cultured cells. These mutations prevent GPI anchors from forming. Without these anchors, specific markers on the exterior of cells will not be present. This assay measures the frequency of cells without these surface markers, also known as “Pig-a mutant cells”.

In Vitro MutaFlow kits use flow cytometry to quickly and reproducibly measure these cells.

Obesity Linked to Cancer

Using MicroFlow and MutaFlow kits,
researchers at Tulane University found diet-induced obesity
increased baseline micronucleus and mutation values.

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